MCQ – 89216

Question

A 13-year-old girl is brought to the physician by her mother for her yearly physical examination. Her temperature is 36.7 C (98 F), blood pressure is 152/91 mm Hg, the pulse is 75/min, and respirations are 18/min. Physical examination shows a lack of secondary sexual characteristics and pelvic examination shows a blind vagina. Laboratory studies reveal hypokalemia and low testosterone and estradiol levels. The cytogenetic analysis shows a 46, XY karyotype. Which of the following enzymes is most likely to be deficient in this patient:

A.

11β-hydroxylase deficiency

B.

5a-reductase

C.

17α-hydroxylase

D.

21-hydroxylase deficiency

Show Answer

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