Varicella-zoster encephalitis with fulminant viral hepatitis
Disseminated varicella with secondary bacterial infections
Ans. C. Reye’s Syndrome
Reye’s syndrome is a rare but serious complication that occurs after administration of aspirin in underlying/recovering viral infections like varicella, influenza, etc. Rarely inborn errors of metabolism can also cause Reyes syndrome. It is an acute non-inflammatory encephalopathy with degenerative live failure. Conservative management including mannitol, fluid management, and broad-spectrum antibiotics helps in managing such cases. Emphasis on preventing this condition should be made by avoiding aspirin use in viral infections.