Question
A year-old boy on day 7 of chickenpox develops jaundice, seizures and delirium.O/E, the GCS is 8(E2V3M3), HR of 42bpm, BP-142/100mmhg, brisk reflexes, and generalized hypertonia and posturing. An emergency CT scan was done and it was suggestive of diffuse cerebral edema.USG abdomen showed mild hepatomegaly with increased echotexture of the liver. Lab parameters show hyperammonemia, metabolic acidosis, moderately elevated liver enzymes, bilirubin, and deranged coagulation profile. What is the most likely diagnosis?
| A. |
Varicella-zoster encephalitis with fulminant viral hepatitis |
| B. |
Wilson disease |
| C. |
Reye’s syndrome |
| D. |
Disseminated varicella with secondary bacterial infections |
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