MCQ – 89303

High anion gap acidosis is seen in all except?

Correct Answer � D Explanation

Ans. D. Respiratory disorders.

• High anion gap metabolic acidosis (HAGMA) is a subcategory of metabolic acidosis (i.e., non-respiratory) etiology. The use of  “GOLD MARK” has gained popularity for its focus on causes common to the 21st century.

• Glycols (ethylene glycol, propylene glycol)

• Oxoproline (pyroglutamic acid, the toxic metabolite of excessive acetaminophen or paracetamol)

• L-Lactate (standard lactic acid seen in lactic acidosis)

• D-Lactate (exogenous lactic acid produced by gut bacteria)

• Methanol (this is inclusive of alcohols in general)

• Aspirin (salicylic acid)

• Renal Failure (uremic acidosis)

• Ketones (diabetic, alcoholic and starvation ketosis).