Question
The Nigro regimen is used in?
| A. |
Carcinoma of the anal canal
|
| B. |
Carcinoma of the colon
|
| C. |
Carcinoma of bladder
|
| D. |
All of the above
|
Show Answer
[ads id=”53026″]
|
Correct Answer � A
Explanation
|
|
Ans. A. Carcinoma of anal canal
-
In May of 1974, Dr. Norman Nigro at Wayne State University published a series in Diseases of the Colon and Rectum of three patients with anal cancer treated with combined chemotherapy and radiation.
-
Dr. Nigro’s protocol of 3000 rads of external beam radiation, a five-day infusion of 5-fluorouricil, and a single injection of mitomycin-C became known as the “Nigro Protocol” and later signified a major advancement in the treatment of anal cancer, and in oncology in general.
-
Further refinements would lead to combined chemotherapy and radiation as the primary treatment for anal carcinoma with most patients successfully treated without surgery.
Like this:
Like Loading...
