MCQ – 89390

 Most common drawback of this instrument is-

Correct Answer � C Explanation

Answer- C Drug deposited in oropharynx

A metered dose inhaler (MDI) is a handheld aerosol device that uses a propellant to deliver the therapeutic agent. MDIs include a pressurized metal canister that contains the following :

• Pharmacologic agent in suspension or solution

• Surfactant

• Propellant

Metering valve

Advantages of MDIs are as follows:

• Portability

• Multidose delivery capability

• Lower risk of bacterial contamination 

Disadvantages of MDIs are as follows:

• Need for correct actuation and inhalation coordination

• Oropharyngeal drug deposition

• Possible flammability of hydrofluoroalkane (HFA) propellants