Adrenocortical Carcinoma

Adrenocortical Carcinoma

Q. 1

Which of the following is true regarding adrenocortical carcinomas:

 A

Increased urinary excretion of VMA

 B

Does not cause metastasis

 C

Surgery is mainstay treatment

 D

Associated with Li-Fraumeni syndrome

Q. 1

Which of the following is true regarding adrenocortical carcinomas:

 A

Increased urinary excretion of VMA

 B

Does not cause metastasis

 C

Surgery is mainstay treatment

 D

Associated with Li-Fraumeni syndrome

Ans. C:D

Explanation:

Answer- (C) Surgery is mainstay treatment (D) Associated with Li-Fraumeni syndrome

Increased VMA excretion into the urine can occur in Neuroblastomas, pheochromocytomas, and other neuroendocrine tumors.

Two rare inherited causes of adrenal cortical carcinomas are Li-Fraumeni syndtome and Beckwith- Wiedenann syndrome.

Metastases to regional and periaortic nodes arc common.

ACC carries a poor prognosis and cure can be achieved only by complete surgical removal.

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