Dengue Fever

Dengue Fever

Q. 1

Tourniquet test is used in the diagnosis of:

 A

Dengue

 B

Scurvy

 C

Malaria

 D

Hypertension

Q. 1

Tourniquet test is used in the diagnosis of:

 A

Dengue

 B

Scurvy

 C

Malaria

 D

Hypertension

Ans. A

Explanation:

Tourniquet test is used in diagnosis of dengue haemorrhagic syndrome (DHS).

The test is performed using a blood pressure cuff which is inflated to a point midway between the systolic and the diastolic blood pressure for 5 minutes.

In DHS, test usually gives a positive result, i.e more than 20 petechiae per 2.5 square cm.

Ref: Park 21st edition, page: 227.


Q. 2

Which of the following does NOT belong to group B Arbo virus?

 A

Dengue virus

 B

Japanese encephalitis virus

 C

West Nile virus

 D

Chikungunya virus

Q. 2

Which of the following does NOT belong to group B Arbo virus?

 A

Dengue virus

 B

Japanese encephalitis virus

 C

West Nile virus

 D

Chikungunya virus

Ans. D

Explanation:

Group A arbovirus include:

  • Chikungunya
  • Sindbis
Group B Arbovirus include:
  • Dengue
  • KFD
  • Japanese Encephalitis
  • West Nile
Ref: Park 21st edition, page 260.

Q. 3

Immediate treatment of choice for severe hypotension in Dengue shock syndrome?

 A

IV crystalloids

 B

Dexamethasone

 C

Noradrenaline

 D

Dopamine

Q. 3

Immediate treatment of choice for severe hypotension in Dengue shock syndrome?

 A

IV crystalloids

 B

Dexamethasone

 C

Noradrenaline

 D

Dopamine

Ans. A

Explanation:

Dengue hemorrhagic fever, a rare complication of dengue fever, characterized by high fever, damage to lymph and blood vessels, bleeding from the nose and gums, enlargement of the liver, and failure of the circulatory system.

The symptoms may progress to massive bleeding, shock, and death.

This is called dengue shock syndrome (DSS).

Here plasma volume replacement is most urgent, IV crystalloids are used for that purpose.


Q. 4

Which of the statements are True/False regarding dengue fever? 

a) All four distinct dengue viruses have Aedes aegypti as their principal vector.
b) A. aegypti usually inhabits dwellings and bites during the day.
c) Severe myalgia that gave rise to the colloquial designation “break-bone fever”.
d) A macular rash on the first day as well as adenopathy, palatal vesicles, and scleral injection.
e) Epistaxis and scattered petechiae are  features of complicated dengue.

 A

a,b,c,d,e-True & None-False

 B

a,b,c-True & d,e-False

 C

a,b,c,d-True & e-False

 D

a,b,e-True & c,d,-False

Q. 4

Which of the statements are True/False regarding dengue fever? 

a) All four distinct dengue viruses have Aedes aegypti as their principal vector.
b) A. aegypti usually inhabits dwellings and bites during the day.
c) Severe myalgia that gave rise to the colloquial designation “break-bone fever”.
d) A macular rash on the first day as well as adenopathy, palatal vesicles, and scleral injection.
e) Epistaxis and scattered petechiae are  features of complicated dengue.

 A

a,b,c,d,e-True & None-False

 B

a,b,c-True & d,e-False

 C

a,b,c,d-True & e-False

 D

a,b,e-True & c,d,-False

Ans. C

Explanation:

Epistaxis and scattered petechiae are often noted in uncomplicated dengue.

Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 1621


Q. 5

Which is enveloped virus – 

 A

Dengue virus

 B

Norwalk virus

 C

Hep A virus

 D

Adenovirus

Q. 5

Which is enveloped virus – 

 A

Dengue virus

 B

Norwalk virus

 C

Hep A virus

 D

Adenovirus

Ans. A

Explanation:

Ans. is ‘a’ i.e., Dengue virus 

  • Dengue virus (a member of flavivirodae) is an enveloped virus.
  • Adenovirus, norwalk virus (calciviridae) and hepatitis A virus (Picornaviridae) are non-enveloped viruses.

Q. 6

Group B (flaviviruses) Arboviruses is/are‑

 A

Dengue fever

 B

Rift valley fever

 C

Chikungunya fever

 D

b and c

Q. 6

Group B (flaviviruses) Arboviruses is/are‑

 A

Dengue fever

 B

Rift valley fever

 C

Chikungunya fever

 D

b and c

Ans. A

Explanation:

Ans. is ‘a’ i.e., Dengue fever


Q. 7

Most virulent dengue fever strain is ‑

 A

1

 B

2

 C

3

 D

4

Q. 7

Most virulent dengue fever strain is ‑

 A

1

 B

2

 C

3

 D

4

Ans. B

Explanation:

Ans. is ‘b’ i.e., 2

“Dengue type-2 strain is being considered to be more virulent strain”.


Q. 8

Most sensitive diagnostic test for dengue is ?

 A

IgM ELISA

 B

Complement fixation test

 C

Neutralization test

 D

Electron microscopy

Q. 8

Most sensitive diagnostic test for dengue is ?

 A

IgM ELISA

 B

Complement fixation test

 C

Neutralization test

 D

Electron microscopy

Ans. C

Explanation:

Ans. is ‘c’ i.e., Neutralization test

DIAGNOSIS OF DENGUE FEVER

.The diagnosis of dengue fever can be made by ‑

A)   Clinical diagnosis

B) Laboratory diagnosis


Q. 9

Vector borne diseases are –

 A

Syphilis

 B

Typhus

 C

Dengue

 D

b and c

Q. 9

Vector borne diseases are –

 A

Syphilis

 B

Typhus

 C

Dengue

 D

b and c

Ans. D

Explanation:

Ans. is ‘b’ i.e., Typhus; ‘c’ i.e., Dengue


Q. 10

All are caused by common vectors, except 

 A

Dengue fever

 B

Yellow fever

 C

KED

 D

Japanese encephalitis

Q. 10

All are caused by common vectors, except 

 A

Dengue fever

 B

Yellow fever

 C

KED

 D

Japanese encephalitis

Ans. C

Explanation:

Ans. is ‘c’ i.e., KFD 

o KFD is transmitted by hard tick where as all else are transmitted by mosquitoes.



Q. 11

Not true about aedes mosquito-

 A

Are recurrent day time biters

 B

Eggs cannot survive more than 1 week without water

 C

Transmits dengue fever

 D

Prefer breeding in stagnant water

Q. 11

Not true about aedes mosquito-

 A

Are recurrent day time biters

 B

Eggs cannot survive more than 1 week without water

 C

Transmits dengue fever

 D

Prefer breeding in stagnant water

Ans. B

Explanation:

Ans. is `b’ i.e., Eggs cannot survive more than 1 week without water 

o In case of aedes agegyti, moisture is a limiting factor for egg survival with surival at higher humidities and eggs

may hatch even after 16 weeks at higher humidities

About other options

o The female aedes arc fearless biters, and they bite chiefly during the day.

o They bite repeatedly to have 1-3 blood meals.

o Aedes transmits dengue fever.

o Aedes prefer artificial collection of water (stagnant water)


Q. 12

Blanket/ mass treatment is indicated in all EXCEPT:

September 2004

 A

Trachoma

 B

Malaria

 C

Yaws

 D

Dengue fever

Q. 12

Blanket/ mass treatment is indicated in all EXCEPT:

September 2004

 A

Trachoma

 B

Malaria

 C

Yaws

 D

Dengue fever

Ans. D

Explanation:

Ans. D i.e. Dengue fever


Q. 13

Saddleback/ biphasic fever is seen in:

September 2004

 A

Typhoid

 B

Dengue

 C

Brucellosis

 D

Trench fever

Q. 13

Saddleback/ biphasic fever is seen in:

September 2004

 A

Typhoid

 B

Dengue

 C

Brucellosis

 D

Trench fever

Ans. B

Explanation:

Ans. B i.e. Dengue


Q. 14

Which of the following is spread by aedes mosquitoes:

September 2007

 A

Loa Loa

 B

Malaria

 C

Dengue

 D

Japanese encephalitis

Q. 14

Which of the following is spread by aedes mosquitoes:

September 2007

 A

Loa Loa

 B

Malaria

 C

Dengue

 D

Japanese encephalitis

Ans. C

Explanation:

Ans. C: Dengue

Aedes mosquito spread the following disease:

  1. Chikungunya fever
  2. Yellow fever (Not in India)
  3. Dengue fever
  4. Dengue hemorrhagic fever
  5. Filaria (Not in India)
  6. Rift valley fever

Japanese encephalitis is caused by culex mosquito.


Q. 15

All of the following features are seen in dengue hemorrhagic fever except:           

September 2010

 A

Positive tourniquet test

 B

Platelet counts less than 1 lac

 C

Falling hematocrit value

 D

Acute onset of high fever

Q. 15

All of the following features are seen in dengue hemorrhagic fever except:           

September 2010

 A

Positive tourniquet test

 B

Platelet counts less than 1 lac

 C

Falling hematocrit value

 D

Acute onset of high fever

Ans. C

Explanation:

Ans. C: Falling hematocrit value

The diagnosis of dengue is usually made clinically. The classic picture is high fever with no localising source of infection, a rash with thrombocytopenia and relative leukopenia- low paltelet and WBC count.

Dengue infection can affect many organs and thus may present unusually as liver dysfunction, renal impairment, meningo­encephalitis or gastroenteritis.

  • Fever, headaches, eye pain, severe dizziness and loss of appetite.
  • Hemorrhagic tendency (positive tourniquet test, spontaneous bruising, bleeding from mucosa, gingiva, injection sites, etc.; vomiting blood, or bloody diarrhoea)
  • Thrombocytopenia (<100,000 platelets per mm3 or estimated as less than 3 platelets per high power field)
  • Evidence of plasma leakage (Hematocrit more than 20% higher than expected, or drop in hematocrit of 20% or more from baseline following IV fluid, pleural effusion, ascites, hypoproteinemia)
  • Encephalitic occurrences

Q. 16

True about dengue hemorrhagic fever are all except:

March 2012

 A

Thrombocytopenia

 B

Thrombosis

 C

Lymphadenopathy

 D

Fever

Q. 16

True about dengue hemorrhagic fever are all except:

March 2012

 A

Thrombocytopenia

 B

Thrombosis

 C

Lymphadenopathy

 D

Fever

Ans. B

Explanation:

Ans: B i.e. Thrombosis

Dengue hemorrhagic fever

In mild forms of dengue hemorrhagic fever, there is thrombocytopenia and haemoconcentration

Minor (petechiae, ecchymoses, epistaxis) or major (gastrointestinal or cerebrovascular) haemorrhagic signs may occur in dengue hemorrhagic fever

  • Acute onset presents with fever, backache, arthralgias, generalized pains (break bone fever), relative bradycardia, lymphadenopathy etc.

Q. 17

Not seen in dengue:       

March 2010

 A

Hemorrhagic tendencies

 B

High grade fever

 C

Circulatory problem

 D

Hepato-splenomegaly

Q. 17

Not seen in dengue:       

March 2010

 A

Hemorrhagic tendencies

 B

High grade fever

 C

Circulatory problem

 D

Hepato-splenomegaly

Ans. D

Explanation:

Ans. D: Hepato-splenomegaly

After an incubation period of 2-7 days the signs and symptoms of dengue appear.

Dengue starts with chills, headache, pain upon moving the eyes, and low backache. Painful aching in the legs and joints occurs during the first hours of illness (breakbone fever).

The temperature rises quickly as high as 104° F (40° C), with relative low heart rate and low blood pressure.

The eyes become reddened. A flushing or pale pink rash comes over the face and then disappears.

Fever and other signs of dengue last for two to four days, followed by rapid drop in temperature (defervescence) with profuse sweating. This precedes a period with normal temperature and a sense of well-being that lasts about a day. A second rapid rise in temperature follows. A characteristic rash appears along with the fever and spreads from the extremities to cover the entire body except the face.

Dengue hemorrhagic fever (DHF) is identified by the detection of bleeding tendencies. Hepatomegaly may be present in more severe frank cases of DHF


Q. 18

Diagnosis of Dengue fever can be made earliest by‑

 A

Viral culture

 B

NS – 1 antigen detection

 C

lgG antibody detection

 D

Nucleic acid test

Q. 18

Diagnosis of Dengue fever can be made earliest by‑

 A

Viral culture

 B

NS – 1 antigen detection

 C

lgG antibody detection

 D

Nucleic acid test

Ans. B

Explanation:

Ans. is ‘b’ i.e., NS-1 antigen detection


Q. 19

Dengue hemorrhagic fever is caused by ‑

 A

Infection with more virulent dengue virus

 B

Infection with same dengue virus repeatedly

 C

Infection with dengue virus in immunocompromized host

 D

Infection with more than one dengue virus

Q. 19

Dengue hemorrhagic fever is caused by ‑

 A

Infection with more virulent dengue virus

 B

Infection with same dengue virus repeatedly

 C

Infection with dengue virus in immunocompromized host

 D

Infection with more than one dengue virus

Ans. A

Explanation:

Ans. is `d’ i.e., Infection with more than one dengue virus

DENGUE FEVER

  • Dengue fever is caused by arboviruses (at least 4 serotypes have been recognized)
  • It is transmitted by Aedes (Aedes aegypti is the main vector).
  • The reservoir of infection is both man and mosquito.
  • The transmission cycle is Man-mosquito-man
  • Dengue fever occurs both epidemically and endemically. Epidemics starts in rainy season and are usually explosive.
  • Aedes mosquito becomes infective by feeding on a patient from the day before onset to the 5th day of illness.

Q. 20

Which among the following is not true about the vector shown in photograph below? 

 A

Are recurrent day time biters.

 B

Eggs cannot survive more than 1 week without water.


 C

Transmits dengue fever.

 D

Prefer breeding in stagnant water.

Q. 20

Which among the following is not true about the vector shown in photograph below? 

 A

Are recurrent day time biters.

 B

Eggs cannot survive more than 1 week without water.


 C

Transmits dengue fever.

 D

Prefer breeding in stagnant water.

Ans. B

Explanation:

Ans:B.)Eggs cannot survive more than 1 week without water.

The vector shown in the photograph above represents aedes mosquito.

In case of aedes agegyti, moisture is a limiting factor for egg survival with surival at higher humidities and eggs may hatch even after 16 weeks at higher humidities.

About other options

o The female aedes arc fearless biters, and they bite chiefly during the day.

They bite repeatedly to have 1-3 blood meals.

Aedes transmits dengue fever.

Aedes prefer artificial collection of water (stagnant water).



Q. 21

Which of the following is spread by the vector shown in the photograph below which breeds in clear,stagnant water? 

 A

Loa Loa.

 B

Malaria.

 C

Dengue.

 D

Japanese encephalitis.

Q. 21

Which of the following is spread by the vector shown in the photograph below which breeds in clear,stagnant water? 

 A

Loa Loa.

 B

Malaria.

 C

Dengue.

 D

Japanese encephalitis.

Ans. C

Explanation:

Ans:C.)Dengue.

The vector shown in the photograph above represents aedes mosquitoe.

Aedes mosquito

  • Aedes mosquitoes are visually distinctive because they have noticeable black and white markings on their body and legs.
  • Unlike most other mosquitoes, they are active and bite only during the daytime.
  • They breed in clear,stagnant water.
  • In case of aedes agegyti, moisture is a limiting factor for egg survival with surival at higher humidities and eggs may hatch even after 16 weeks at higher humidities.
  • Aedes mosquito spread the following disease:
    • Chikungunya fever
    • Yellow fever (Not in India)
    • Dengue fever
    • Dengue hemorrhagic fever
    • Filaria (Not in India)
    • Rift valley fever

 



Q. 22

All of the following are true about dengue except:

 A

Lamivudine is the drug of choice

 B

Malnutrition is protective

 C

Aedes aegypti acts as vector

 D

Caused by Flavivirus

Q. 22

All of the following are true about dengue except:

 A

Lamivudine is the drug of choice

 B

Malnutrition is protective

 C

Aedes aegypti acts as vector

 D

Caused by Flavivirus

Ans. A

Explanation:

Ans. a. Lamivudine is the drug of choice


Q. 23

Break bone fever is ‑

 A

Malaria

 B

Dengue fever

 C

Kala azar

 D

Japanese encephalitis

Q. 23

Break bone fever is ‑

 A

Malaria

 B

Dengue fever

 C

Kala azar

 D

Japanese encephalitis

Ans. B

Explanation:

Ans. is ‘b’ i.e., Dengue fever

  • White disease         AIDS
  • Poverty disease → Cholera
  • Hundred day cough: Pertussis (Whooping cough)
  • 5 day fever: Trench fever
  • 8′ day disease: Tetanus
  • Black sickness: Kala azar
  • Black death: Plague
  • Cerebrospinal fever: Meningococcal meningitis
  • Breakbone fever: Dengue
  • Koch’s phenomenon: Tuberculosis
  • Hansen ‘s disease: Leprosy
  • Break-bone fever: Dengue
  • Slim disease: AIDS
  • Monkey fever : KFD
  • First disease/ Rubeolla: Measles
  • Second disease: Scarlet fever
  • Third disease/ German Measles: Rubella
  • Fourth disease: Duke’s disease
  • Fifth disease: Erythema infectiosum (Parvovirus)
  • Sixth disease/ Baby Measles/ 3-day fever: Exanthem subitum/ Roseola infantum
  • Barometer of Social Welfare (India): Tuberculosis
  • Father of Public Health: Cholera
  • River Blindness: Onchocerciasis


Leave a Reply

%d bloggers like this:
Malcare WordPress Security