Haematopoiesis

Haematopoiesis

Q. 1

In infant, bone marrow biopsy is done from ‑

 A

Sternum

 B

Iliac crest

 C

Tibia

 D

All of above

Q. 1

In infant, bone marrow biopsy is done from ‑

 A

Sternum

 B

Iliac crest

 C

Tibia

 D

All of above

Ans. C

Explanation:

Ans. is ‘c’ i.e., Tibia

Sternum : —>

  • Hematopoitically active
  • Site in cooperative patient like adult

Ilium :

  • Apprehesive patient
  • Useful in older children & adult

Tibia :

  • Useful in newborn & infant and children below 2 year of age.

Q. 2

Small round cell tumors ‑

 A

Wilm’s tumor

 B

Retinoblastoma

 C

Rhabdomyosarcoma

 D

All

Q. 2

Small round cell tumors ‑

 A

Wilm’s tumor

 B

Retinoblastoma

 C

Rhabdomyosarcoma

 D

All

Ans. D

Explanation:

Ans. is ‘d’ i.e., All 

Small round blue cell tumors

  • Histologically many of the malignant pediatric neoplasms are unique.
  • They tend to have a more primitive (embryonal) rather than pleomorphic anaplastic microscopic appearance. 
  • Often characterized by sheets of cells with small round nuclei.
  • Frequently exhibit features of organogenesis specific to the site of tumour origin (therefore these tumours are frequently designated by suffix – blastoma).
  • Owing to their primitive histological appearance many childhood tumours have been collectively refered to as small round blue cell tumours.

The differential diagnosis of small round blue cell tumours includes

Neuroblastoma Rhabdomyosarcoma

Retinoblastoma

Wilms tumours Ewings sarcoma Medulloblastoma
Lymphoma Primitive neuroectodermal tumours Burkitt lymphoma



Q. 3

Ratio of fat cells and blood cells in bone marrow is ‑

 A

1:4

 B

1 : 2

 C

1 : 1

 D

2 : 1

Q. 3

Ratio of fat cells and blood cells in bone marrow is ‑

 A

1:4

 B

1 : 2

 C

1 : 1

 D

2 : 1

Ans. C

Explanation:

Ans. is ‘c’ i.e., 1:1 

  • In normal adults, the ratio of fat cells to hematopoietic cells is about 1:1.
  • In bone marrow, myeloid to erythroid ratio is 3:1 or 4:1.4

Quiz In Between



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