Mumps Virus

Mumps Virus

Q. 1

Which is the commonest complication of Mumps in adults ?

 A

Encephalitis

 B

Orchitis

 C

Pancreatitis

 D

Carditis

Q. 1

Which is the commonest complication of Mumps in adults ?

 A

Encephalitis

 B

Orchitis

 C

Pancreatitis

 D

Carditis

Ans. B

Explanation:

Meningoencephalitis is common in children.  Unilateral deafness and thyroiditis are also known complication.


Q. 2

Most common viral cause of acquired aqueductal stenosis is ?

 A

Rubella

 B

Mumps

 C

Toxoplasma

 D

Enterovirus

Q. 2

Most common viral cause of acquired aqueductal stenosis is ?

 A

Rubella

 B

Mumps

 C

Toxoplasma

 D

Enterovirus

Ans. B

Explanation:

Ans. is ‘b’ i.e., Mumps

o Out of the given options, only mumps and toxoplasma cause aqueductal stenosis. Toxoplasma is not a virus. Hence, the answer is mumps.


Q. 3

Which of the following is true of mumps ‑

 A

Salivary gland involvement is limited to the parotids

 B

The patient is not infectious prior to clinical parotid enlargement

 C

Menigoencephalitis can precede parotitis

 D

Mumps orchitis frequently leads to infertility

Q. 3

Which of the following is true of mumps ‑

 A

Salivary gland involvement is limited to the parotids

 B

The patient is not infectious prior to clinical parotid enlargement

 C

Menigoencephalitis can precede parotitis

 D

Mumps orchitis frequently leads to infertility

Ans. C

Explanation:

Ans. is ‘c’ i.e., Meningoencephalitis can precede parotitis

“Aseptic meningitis may develop before, during, after or in the absence of parotitis.”

About other options

o Mainly parotid glands are involved, but sublingual and submaxillary glands may also be involved. o Patient is infectious 4-6 days before the onset of swelling.

Sterility after mumps orchitis is rare.


Q. 4

Which of the following vaccine should not be given during pregnancy ?-

 A

HBV

 B

Measles, mumps, rubella

 C

Typhoid

 D

Cholera

Q. 4

Which of the following vaccine should not be given during pregnancy ?-

 A

HBV

 B

Measles, mumps, rubella

 C

Typhoid

 D

Cholera

Ans. B

Explanation:

Ans. is ‘b’ i.e., Measles, mumps, rebella 


Q. 5

Strain used in mumps vaccine?

 A

Edmonsten Zagreb 

 B

Oka

 C

Jeryl Lynn

 D

Danish 1331

Q. 5

Strain used in mumps vaccine?

 A

Edmonsten Zagreb 

 B

Oka

 C

Jeryl Lynn

 D

Danish 1331

Ans. C

Explanation:

Ans. is ‘c’ i.e., Jeryl Lynn 


Q. 6

Most common viral disease affecting parotid glands –

 A

Mumps

 B

Measles

 C

Rubella

 D

Varicella

Q. 6

Most common viral disease affecting parotid glands –

 A

Mumps

 B

Measles

 C

Rubella

 D

Varicella

Ans. A

Explanation:

Ans. is ‘a’ i.e., Mumps 

o Amongst the given options, mumps affect salivary glands most commonly.


Q. 7

In mumps the most common eye lesion is:

 A

Dacryoadenitis

 B

Uveitis

 C

Membranous conjunctivitis

 D

Chorioretinitis

Q. 7

In mumps the most common eye lesion is:

 A

Dacryoadenitis

 B

Uveitis

 C

Membranous conjunctivitis

 D

Chorioretinitis

Ans. A

Explanation:

Ans. Dacryoadenitis


Q. 8

Mumps most commonly affects the:    

March 2004

 A

Parotid gland

 B

Submandibular gland

 C

Sublingual gland

 D

Lacrimal gland

Q. 8

Mumps most commonly affects the:    

March 2004

 A

Parotid gland

 B

Submandibular gland

 C

Sublingual gland

 D

Lacrimal gland

Ans. A

Explanation:

Ans. A i.e. Parotid gland


Q. 9

Which of the following is not a complication of mumps: 

March 2009

 A

Orchitis

 B

Oophoritis

 C

Encephalitis

 D

None

Q. 9

Which of the following is not a complication of mumps: 

March 2009

 A

Orchitis

 B

Oophoritis

 C

Encephalitis

 D

None

Ans. D

Explanation:

Ans. D i.e. None of the option

Known complications of mumps include:

  • Mumps viral infections in adolescent and adult males carry an up to 30% risk that the testes may become infected (orchitis or epididymitis), which can be quite painful; about half of these infections result in testicular atrophy, and in rare cases sterility can follow.
  • Spontaneous abortion in about 27% of cases during the first trimester of pregnancy.
  • Mild forms of meningitis in up to 10% of cases (40% of cases occur without parotid swelling)
  • Oophoritis (inflammation of ovaries) in about 5% of adolescent and adult females, but fertility is rarely affected.
  • Pancreatitis in about 4% of cases, manifesting as abdominal pain and vomiting
  • Encephalitis (very rare, and fatal in about 1% of the cases when it occurs)
  • Profound (91 dB or more) but rare sensorineural hearing loss, uni- or bilateral. Acute unilateral deafness occurs in about 0.005% of cases
  • Thyroiditis, neuritis, hepatitis, myocarditis etc.

Q. 10

Which of the following is not true about Mumps:

March 2007

 A

Caused by paramyxovirus

 B

Incubation period is less than 14 days

 C

Orchitis is a common complication in males

 D

Aseptic meningitis is a commoner complication in children

Q. 10

Which of the following is not true about Mumps:

March 2007

 A

Caused by paramyxovirus

 B

Incubation period is less than 14 days

 C

Orchitis is a common complication in males

 D

Aseptic meningitis is a commoner complication in children

Ans. B

Explanation:

Ans. B: Incubation period is less than 14

Incubation period of mumps is 14-18 days The more common symptoms of mumps are:

  • Parotid inflammation/ parotitis in 60-70% of infections.
  • Fever
  • Headache
  • Orchitis, referring to painful inflammation of the testicle.Males past puberty who develop mumps have a 30 percent risk of orchitis.

There is no specific treatment for mumps.

Mumps viral infections in adult males carries a 25% risk that the testes may become infected which in rare cases leads to sterility.

After the illness, life-long immunity to mumps generally occurs.

Complications

  • Infection of other organ systems
  • Sterility in men (this is quite rare, and mostly occurs in older men)
  • Mild forms of meningitis (rare, 40% of cases occur without parotid swelling)
  • Encephalitis (very rare, rarely fatal)
  • Profound (91 dB or more) but rare sensorineural hearing loss, uni- or bilateral
  • Pancreatitis manifesting as pain abdomen and vomiting
  • Oophoritis (inflammation of ovaries) but fertility is rarely affected.

Q. 11

True about mumps vaccine ‑

 A

Killed vaccine

 B

Efficacy 95%

 C

Only one dose is given

 D

Not combined with other vaccines

Q. 11

True about mumps vaccine ‑

 A

Killed vaccine

 B

Efficacy 95%

 C

Only one dose is given

 D

Not combined with other vaccines

Ans. B

Explanation:

Ans. is ‘b’ i.e., Efficacy 95%

Mumps vaccine

  • Highly effective live attenuated vaccine is now available for the prevention of mumps.
  • Widely-used live attenuated mumps vaccine strains include the Jeryl-Lynn, RIT 4385, Leningrad-3, L-Zagreb and Urabe strains.
  • Live attenuated mumps vaccine strains used only on a limited scale include the Hoshino, Torii and NKM-46 strains.
  • The WHO recommends that the Rubini mumps vaccine strain should not be used in national immunization programmes because of its demonstrated low effectiveness.
  • A single dose (0-5 ml) intramuscularly produces detectable antibodies in 95% of vaccines.
  • The duration of long-term immunity is not known.
  • It is recommended for routine immunization for children over 1 year of age, either alone or in combination with other virus vaccines, e.g. in MMR vaccine or as a quadrivalent vaccine with varicella.
  • A second dose is recommended for children at 4-6 years of age i.e., before starting the school.
  • The current mumps strain (Jeryl Lynm) has the lowest associated incidence of post vaccine aseptic meningitis (from 1 in 150,000 to 1 in 1.8 million).
  • There are no known case of long-term sequelae associated with mumps vaccination.

Q. 12

Most common presentation of mumps ‑

 A

Pain and lacrimation of eye

 B

Pain and swelling of parotid glands

 C

Pain and swelling of submandibular and sublingual glands

 D

Aseptic meningitis

Q. 12

Most common presentation of mumps ‑

 A

Pain and lacrimation of eye

 B

Pain and swelling of parotid glands

 C

Pain and swelling of submandibular and sublingual glands

 D

Aseptic meningitis

Ans. B

Explanation:

Ans. is ‘b’ i.e., Pain and swelling of parotid glands


Q. 13

Most common manifestation of mumps in adult males –

 A

Aseptic meningitis

 B

Encephalitis

 C

Orchitis

 D

Sinusitis

Q. 13

Most common manifestation of mumps in adult males –

 A

Aseptic meningitis

 B

Encephalitis

 C

Orchitis

 D

Sinusitis

Ans. C

Explanation:

Ans. is ‘c’ i.e., Orchitis

Orchitis is the most common manifestation of mumps among postpubertal males.


Q. 14

 

A 10 year old boy suffered from fever,headache and then bilteral enlargement of the following glands.There was a similar complain with one of the family member before.What would be the most probable infecting agent?

 A

Varicella virus

 B

Streptococcus

 C

 Mumps virus

 D

Staphylococcus

Q. 14

 

A 10 year old boy suffered from fever,headache and then bilteral enlargement of the following glands.There was a similar complain with one of the family member before.What would be the most probable infecting agent?

 A

Varicella virus

 B

Streptococcus

 C

 Mumps virus

 D

Staphylococcus

Ans. C

Explanation:

Ans:C.)Mumps virus

Gland shown in the image is Parotid gland.

Mumps

  • Mumps, also known as epidemic parotitis, is a viral disease caused by the mumps virus.
  • Mumps is highly contagious and spreads rapidly among people living in close quarters.The virus is transmitted by respiratory droplets or direct contact with an infected person.

  • Initial symptoms include fever, muscle pain, headache, and feeling tired.This is then usually followed by painful swelling of mostly both parotid salivary glands.
  • Symptoms typically occur 16 to 18 days after exposure and resolve after seven to ten days.
  • Complications like Orchitis,Meningoencephalitis,pancreatits.
  • Mumps is preventable by the mumps vaccine.



Q. 15

Unilateral sensorineural hearing loss may occur in‑

 A

Coronavirus

 B

Mumps

 C

Pertussis

 D

Rotavirus

Q. 15

Unilateral sensorineural hearing loss may occur in‑

 A

Coronavirus

 B

Mumps

 C

Pertussis

 D

Rotavirus

Ans. B

Explanation:

Ans. is ‘b i.e., Mumps 

Infections of labyrinth

Trauma to labyrinth or VIII nerve (Head injury, surgery etc)

Noise induced hearing loss

Ototoxic drugs

Acquired causes of SNHL

Presbycusis

Meniere’s disease

Acoustic neuroma

Sudden hearing loss

Systemic disorders

(DM, Hypothyroidism, Renal disorders)

Multiple sclerosis

Smoking & Alcoholism



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