Nocardia

Nocardia

Q. 1 True about Nocardia is all except
 A Most commonly causes pneumonia
 B Is aerobic
 C Acid fast properties
 D Pencillin is the drug of choice
Q. 1 True about Nocardia is all except
 A Most commonly causes pneumonia
 B Is aerobic
 C Acid fast properties
 D Pencillin is the drug of choice
Ans. D

Explanation:

Pencillin is the drug of choice


Q. 2

A 50 year old man presents to the clinic with multiple abcesses and discharging sinus present on his left foot. X-ray of the foot shows destructive changes in the underlying bone. Which of the following is the most likely causative organism?

 A

Nocardia

 B

Sporothrix schenkii

 C

Histoplasmosis

 D

Cryptospordiosis

Q. 2

A 50 year old man presents to the clinic with multiple abcesses and discharging sinus present on his left foot. X-ray of the foot shows destructive changes in the underlying bone. Which of the following is the most likely causative organism?

 A

Nocardia

 B

Sporothrix schenkii

 C

Histoplasmosis

 D

Cryptospordiosis

Ans. A

Explanation:

Patient in this question is most likely suffering from Actinomycotic mycetoma caused by Nocardia and Actinomadura species.

Disease begins as a papule or a nodule and slowly progress into multiple abcesses and sinus tracts ramifying deep into the tissue.

Trimethoprim sulfamethoxazole or dapsone are effective in the treatment.


Q. 3

All are true about disseminated nocardial infection, EXCEPT:

 A

The most common site of dissemination is liver

 B

The typical manifestation is subacute abscess

 C

Brain abscess are usually supratentorial

 D

Sulfonamides are the drug of choice

Q. 3

All are true about disseminated nocardial infection, EXCEPT:

 A

The most common site of dissemination is liver

 B

The typical manifestation is subacute abscess

 C

Brain abscess are usually supratentorial

 D

Sulfonamides are the drug of choice

Ans. A

Explanation:

The most common site of dissemination in nocardiosis is the brain.

 
The typical manifestation of extrapulmonary dissemination is a subacute abscess. In CNS infections, brain abscesses are usually supratentorial, are often multiloculated.Sulfonamides are the drug of choice.
 
Ref: Harrisons Principles of Internal Medicine, 18th Edition, Pages 1323-25

 


Q. 4

A clinical specimen was obtained from the wound of a patient diagnosed as Nocardiosis. For the selective isolation of Nocardia sp. which one of the following would be the best method –

 A

Paraffin bait technique

 B

Castaneda’s culture method

 C

Craige’s tube method

 D

All

Q. 4

A clinical specimen was obtained from the wound of a patient diagnosed as Nocardiosis. For the selective isolation of Nocardia sp. which one of the following would be the best method –

 A

Paraffin bait technique

 B

Castaneda’s culture method

 C

Craige’s tube method

 D

All

Ans. A

Explanation:

Ans. is ‘a’ i.e., Paraffin bait technique 

.  Since nocardiae are among the few aerobic microorganism that use paraffin as a carbon source, paraffin baiting can be used to isolate the organism from mixed culture.


Q. 5

Nocardia is stained by all except – 

 A

Acid fast stain

 B

Kiram’s stain

 C

Alcian blue stain

 D

Mucin stain

Q. 5

Nocardia is stained by all except – 

 A

Acid fast stain

 B

Kiram’s stain

 C

Alcian blue stain

 D

Mucin stain

Ans. B

Explanation:

Ans. is ‘b’ i.e., Kiram’s stain 

.  Nocardia is an acid fast organism.

.   Acid fast stains commonly used for staining of nocardia are ‑

i)        Ziehl – Neelson stain

ii)      Kinyon acid fast stain

iii)    Fite faraco stain

.  Mucin stains can also stain nocardia. Examples of mucin stain are ‑

i)          

Mucicarmine stain

ii)       Alcian blue stain


Q. 6

Nocardia can be differentiated from other Actinomyces by ?

 A

ZN staining

 B

Fontana stain

 C

Gram staining

 D

All

Q. 6

Nocardia can be differentiated from other Actinomyces by ?

 A

ZN staining

 B

Fontana stain

 C

Gram staining

 D

All

Ans. A

Explanation:

Ans. is ‘a’ i.e., ZN staining 


Q. 7

A patient presents to the emergency department with history of persistent fever & cough. Radiological features are suggestive of pneumonia. Sputum examination cultures reveal aerobic branching Gram positive filaments that are partially acid fast.Which of the following is the most likely etiological agent –

 A

Actinomyces israeli

 B

Nocardia asteriodes

 C

Aspergillus fumigatus

 D

Staphylococcus aureus

Q. 7

A patient presents to the emergency department with history of persistent fever & cough. Radiological features are suggestive of pneumonia. Sputum examination cultures reveal aerobic branching Gram positive filaments that are partially acid fast.Which of the following is the most likely etiological agent –

 A

Actinomyces israeli

 B

Nocardia asteriodes

 C

Aspergillus fumigatus

 D

Staphylococcus aureus

Ans. B

Explanation:

Ans. is ‘b’ i.e., Nocardia asteroides

.  Information in this question are :‑

i)         Aerobic organism.

ii)       Branching filament.

iii)      Gram positive

iv)     Partially acid fast

v)       Patient has pneumonia

  • Among the given options only Nocardia asteroides is acid fast. Nocardia is strict aerobe, acid fast, Gram positive and branching beaded filamentous. Most common clinical manifestation of Nocardia is pneumonia.

Q. 8

A charachteristic infection of Nocardia Asteroides is –

 A

Diarrhea

 B

Secondary Dissemination to liver

 C

Brain Abscess

 D

Colonic Diverticulosis

Q. 8

A charachteristic infection of Nocardia Asteroides is –

 A

Diarrhea

 B

Secondary Dissemination to liver

 C

Brain Abscess

 D

Colonic Diverticulosis

Ans. C

Explanation:

Ans. is ‘c’ i.e., Brain Abscess 

  • Brain Abscess is the most charachteristic infection of Nocardia Asterodies amongst the options provided.

The most common site of dissemination of nocardiosis is the brain, The typical manifestation is a subacute brain abscess’.

  • The most charachteristic infection of Nocardia Asterodies is Respiratory Tract Disease in the form of subacute pneumonia (Not provided amongst options).

Q. 9

Nocardia resemble actinomyces morphological but- 

 A

Are anaerobic 

 B

Are faculative anaerobic

 C

Are aerobic

 D

Require CO, for growth

Q. 9

Nocardia resemble actinomyces morphological but- 

 A

Are anaerobic 

 B

Are faculative anaerobic

 C

Are aerobic

 D

Require CO, for growth

Ans. C

Explanation:

Ans. is ‘c’ i.e., Are aerobic 


Q. 10

The causative organism in Madura Mycosis Mycetoma is –

 A

Nocardia

 B

Dimorphic fungus

 C

Aspergillus

 D

Dermatophytes

Q. 10

The causative organism in Madura Mycosis Mycetoma is –

 A

Nocardia

 B

Dimorphic fungus

 C

Aspergillus

 D

Dermatophytes

Ans. A

Explanation:

Ans. is ‘a’ i.e., Nocardia

.    Mycetoma can be caused by both fungus and bacteria.

Mycetoma

Actinomycetoma                                                Eumycetoma

.       Caused by bacteria:                               . Caused by fungus:

–       Nocardia                                                    – Madurella mycetomatis

–      Actinomadura                                          – Pseudo-allescheria boydii

–      Streptomyces                                            – Philophora

–     Actinomyces

.       Grains are thin                                        . Grains are broad and show septae and chlamydospores

.       Granules are white to yellow                . Granules are black


Q. 11

Actinomycetoma is caused by-

 A

Actinomyces

 B

Nocardias

 C

Streptomyces

 D

All

Q. 11

Actinomycetoma is caused by-

 A

Actinomyces

 B

Nocardias

 C

Streptomyces

 D

All

Ans. D

Explanation:

Ans. is ‘a’ i.e., Actinomyces; ‘b’ i.e., Nocardia; ‘c’ i.e., Streptomyces


Q. 12

A patient is suffering from pneumonia. Laboratory study shows acid-fast filamentous bacterium. The causative organism is ‑

 A

M. tuberculosis

 B

Actinomyces

 C

Nocardia

 D

Mycobacterium Avium intracellulare

Q. 12

A patient is suffering from pneumonia. Laboratory study shows acid-fast filamentous bacterium. The causative organism is ‑

 A

M. tuberculosis

 B

Actinomyces

 C

Nocardia

 D

Mycobacterium Avium intracellulare

Ans. C

Explanation:

Ans. is ‘c’ i.e., Nocardia

Symptoms of pneumonia by a filamentous acid fast bacterium suggest the diagnosis of Nocardia.


Q. 13

A 36 years male presented with complain of productive cough and fever for last 2 months. He has undergone kidney transplantation 2 years back. His sputum examination revealed a gram positive filamentous bacteria that showed acid fastness with modified Ziehl-Neelsen staining (1% H2SO4). The most likely etiological agent is ?

 A

Actinomyces israelii

 B

Nocardia asteroides

 C

Blastomyces dermaiiiidis

 D

Crfptosperidium parvum

Q. 13

A 36 years male presented with complain of productive cough and fever for last 2 months. He has undergone kidney transplantation 2 years back. His sputum examination revealed a gram positive filamentous bacteria that showed acid fastness with modified Ziehl-Neelsen staining (1% H2SO4). The most likely etiological agent is ?

 A

Actinomyces israelii

 B

Nocardia asteroides

 C

Blastomyces dermaiiiidis

 D

Crfptosperidium parvum

Ans. B

Explanation:

Ans. is ‘b’ i.e., Nocardia asteroides 



Leave a Reply

%d bloggers like this:
Malcare WordPress Security