Tag: Inflammatory Bowel Disease

Inflammatory Bowel Disease

INFLAMMATORY BOWEL DISEASE

Q. 1

A 28 year old female with a several-year history of intermittent diarrhea and abdominal pain is seen for inflammatory bowel disease. Endoscopic evaluation of her terminal ileum, colon, and rectum is undertaken. Which of the following endoscopic observations is more indicative of Crohn’s disease than of ulcerative colitis?

 A

Discontinuous mucosal involvement

 B

Mucosal atrophy

 C

Mucosal ulceration

 D

Pseudopolyps

Q. 1

A 28 year old female with a several-year history of intermittent diarrhea and abdominal pain is seen for inflammatory bowel disease. Endoscopic evaluation of her terminal ileum, colon, and rectum is undertaken. Which of the following endoscopic observations is more indicative of Crohn’s disease than of ulcerative colitis?

 A

Discontinuous mucosal involvement

 B

Mucosal atrophy

 C

Mucosal ulceration

 D

Pseudopolyps

Ans. A

Explanation:

Crohn’s disease is frequently associated with “skip lesions,” discontinuous areas of active disease in the colon and small intestine with intervening segments that appear normal.
This is in marked contrast to ulcerative colitis, which most commonly shows continuous mucosal involvement.
 
Both ulcerative colitis and Crohn’s disease can show mucosal atrophy. Chronic mucosal inflammation produces glandular atrophy, and a loss of mucosal folding.
 
Mucosal ulceration is seen in both Crohn’s disease and ulcerative colitis. The ulcers of Crohn’s disease are generally described as linear fissures, following the longitudinal axis of the intestine. Ulcerative colitis typically produces broad, extensive areas of ulceration.
 
Pseudopolyps are most commonly associated with ulcerative colitis, and represent the islands of spared mucosa between the broad ulcerations.
 
Ref: Wyatt C., Butterworth IV J.F., Moos P.J., Mackey D.C., Brown T.G. (2008). Chapter 14. Gastrointestinal Pathology. In C. Wyatt, J.F. Butterworth IV, P.J. Moos, D.C. Mackey, T.G. Brown (Eds), Pathology: The Big Picture.

Q. 2

Inflammatory bowel disease with transmural involvement and skip lesions is?

 A

Crohn’s disease

 B

Ulcerative colitis

 C

Shigella infection

 D

Clostridium infection

Q. 2

Inflammatory bowel disease with transmural involvement and skip lesions is?

 A

Crohn’s disease

 B

Ulcerative colitis

 C

Shigella infection

 D

Clostridium infection

Ans. A

Explanation:

Ans. is ‘a’ i.e., Crohn’s disease


Q. 3

Which of the following includes inflammatory bowel disease in children

 A

Coeliac disease

 B

Tropical sprue

 C

Regional ileitis

 D

Cystic fibrosis

Q. 3

Which of the following includes inflammatory bowel disease in children

 A

Coeliac disease

 B

Tropical sprue

 C

Regional ileitis

 D

Cystic fibrosis

Ans. C

Explanation:

Ans. is ‘c’ i.e., Regional ileitis

Inflammatory bowel disease

o Inflammatory bowel disease (IBD) is used to represent two distinct disorders of idiopathic intestinal inflammation :

i) Crohn disease or regional ileitis                                                     ii) Ulcerative colitis

Quiz In Between


Q. 4

Surgical indications in inflammatory bowel diseases are A/E :

 A

Obstruction

 B

Perianal complication

 C

Extraintestinal complication

 D

Stricture

Q. 4

Surgical indications in inflammatory bowel diseases are A/E :

 A

Obstruction

 B

Perianal complication

 C

Extraintestinal complication

 D

Stricture

Ans. C

Explanation:

Ans. is ‘c’ i.e. Extraintestinal complication 

  • Indications of surgery in Ulcerative colitis are mentioned in previous question.
  • Indications of surgery in Crohn’s disease
  • As Crohn’s disease can affect any part of the gastrointestinal tract, its therapeutic rationale is fundamentally different from that of ulcerative colitis.
  • Whereas UC may be cured by removal of the affected intestinal segment (the colon & rectum), the operations in Crohn’s disease are only pallative. The goals of surgery in Crohn’s disease are relief of symptoms, correction of complications and prevention of cancer.
  • Indications of surgery in Crohn’s disease are:

– fistulas (internal fistulas, enterocutaneous fistulas, colovesical & colovaginal fistulas) intra-abdominal abscesses perianal disease

– strictures toxic megacolon and fulminant colitis chronically ill health massive bleeding high grade dysplasia/cancer intractability


Q. 5

Inflammatory bowel disease found in children :

 A

Ulcerative colitis    

 B

Tropical sprue

 C

Crohn’s disease

 D

a and b

Q. 5

Inflammatory bowel disease found in children :

 A

Ulcerative colitis    

 B

Tropical sprue

 C

Crohn’s disease

 D

a and b

Ans. D

Explanation:

Ans. is ‘a’ i.e. Ulcerative colitis & ‘b’ Crohn’s disease 

The term inflammatory bowel ds. includes two diseases : Crohn’s ds. & Ulcerative colitis. The most common time of onset of IBD is during adolescence and young adulthood. However, IBD may begin as early as the 1st year of life.



Q. 6

Extraintestinal manifestations of Inflammatory bowel disease include all of the following, Except:

 A

Uveitis

 B

Sclerosing cholangitis

 C

Osteoarthritis

 D

Skin nodules

Q. 6

Extraintestinal manifestations of Inflammatory bowel disease include all of the following, Except:

 A

Uveitis

 B

Sclerosing cholangitis

 C

Osteoarthritis

 D

Skin nodules

Ans. C

Explanation:

Answer is C (Osteoarthritis):

Osteoarthritis is not an extraintestinal manifestation of inflammatory bowel disease

Uveitis, Sclerosing Cholangitis, and skin nodules (Erythema nodosum) are all recognized extraintestinal manifestations of inflammatory bowel disease.

Quiz In Between



Malcare WordPress Security