Short Quiz on Dumping syndrome

Instruction

1. This Test has 5 Questions 
2. There is 1 Mark for each correct Answer

MCQ – 1

Least chances of complication like dumping syndrome and diarrhoea are seen in the following condition:

Parietal cell vagotomy

Truncal vagotomy & Gastrojejunostomy

Antrectomy with truncal vagotomy

Vagotomy with pyloroplasty

Explanation :

Vagal denervation of just the parietal cell area of the stomach is called parietal cell vagotomy or proximal gastric vagotomy.
The technique spares the nerves of Latarjet but divides all vagal branches that terminate on the proximal two thirds of the stomach. 

 
Parietal cell vagotomy appears to have about the same effectiveness as truncal or selective vagotomy for curing the ulcer disease, but dumping and diarrhea are much less frequent.

It is probably the procedure of choice for intractable and perforated duodenal ulcers and is relatively less useful for obstructing and bleeding ulcers.

The principal disadvantage is recurrent ulceration in about 10% of patients.
 
Ref: Doherty G.M., Way L.W. (2010). Chapter 23. Stomach & Duodenum. In G.M. Doherty (Ed), CURRENT Diagnosis & Treatment: Surgery, 13e.

 


MCQ – 2

Dumping syndrome occurs least with ‑

Selective vagotomy

Truncal vagotomy

Highly selective vagotomy

Syndrome occurs with all of the above commonly

Explanation :

Ans. is ‘c’ i.e., Highly selective vagotomy 
It is least seen with highly selective vagotomy because the motility of the stomach is least affected in highly selective vagotomy and is most common with gastrectomy.


MCQ – 3

Dumping syndrome is due to:

Diarrhoea

Presence of hypertonic content in small intestine

Vagotomy

Reduced gastric capacity

Explanation :

Answer is B (Presence of Hypertonic Contents in small intestine)

DUMPING SYNDROME refers to a syndrome of abdominal and vasomator symptoms which results from dumping of food stuffs with a high osmotic load, front the stomach, into the small bowel.

Loss of storage capacity of stomach and ablation, by pass or destruction of pylorus, results in rapid emptying of hyperostnolar chyme into duodenummm and small intestine. Extracellular fluid then shifts into the intestinal lumen to restore isotonicity resulting in decreased intravascular volume, which gives rise to the vasomotor symptoms. Note that while reduced gastric capacity contributes, option (b) is a more accurate answer.

Dumping Syndrome is actually of two types:

  • Early dumping syndrome (as described above)
  • Late dumping syndrome: This is Reactive hypoglvcemiae. The carbohydrate load in thesmall intestine later causes a rise in plasma glucose, which in turn causes insulin levels to rise causing a secondary hypoglycemia.

MCQ – 4

Which, of the following plays a major role in the development of dumping syndrome:       

Vagolytic mechanism

Smaller stomach

Excessive food in the stomach

Large volume of hyperosmotic fluid in the intestine

Explanation :

Ans. D: Large volume of hyperosmotic fluid in the intestine

  • Dumping syndrome refers to a constellation of post-prandial symptoms occurring due to accelerated emptying (dumping) of hyperosmolar stomach contents into the small bowel.
  • It is usually seen in operation which destroys the pyloric sphincter (i.e gastrectomy, antrectomy and drainage procedures).
  • It occurs immediately after meals (after 15-30 minutes) 
  • Dumping of hyperosmolar contents into the small bowel results in rapid fluid influx from the circulation into the gastrointestinal tract.
  • This leads to acute intestinal distention and peripheral and splanchnic vasodilatation

MCQ – 5

Dumping syndrome is characterized by all of the following except:
March 2005

Colic

Tremors and giddiness

Hyperglycemia

Epigastric fullness 

Explanation :

Answer- C. Hyperglycemia
Dumping syndrome is a relatively rare disorder in which the stomach contents are delivered too quickly to the small intestine.
It occurs as a physiological reaction to the consumption of too much simple or refined sugar in some persons, when simple sugar exits the stomach too rapidly it attracts fluid into the upper intestine, and the blood volume decreases as it attempts to absorb the sugar.
The vasomotor symptoms comprise general weakness, pallor, sweating, palpitation and light headedness.
symptoms of gastrointestinal disturbance such as epigastric discomfort, nausea, vomiting and possibly an episode of diarrhea is observed.

The biochemical changes that occur in dumping syndrome are hyperinsulinaemia followed by hypoglycaemia


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