FOCAL NODULAR HYPERPLASIA
FOCAL NODULAR HYPERPLASIA
- PNH is a benign condition with focal overgrowth of functioning liver tissue supported by fibrous stroma.
- 2nd MC of benign tumour of liver.
CLINICAL FEATURES-
- Patients are middle aged females on OCP
- Hepatic architecture is maintained.
- Asymptomatic
- Multiple nodule present
INVESTIGATIONS-
- Ultrasound shows solid mass
- CECT (IOC) shows central stellate scarring and hypervascular lesion.
- FNH contains hepatocytes & Kupffer cells.
- Angiography- spoke wheel/ cart wheel appearance
- MRI uses liver specific contrast agents to determine hepatocellular origin of FNH-
a) Gadoetic acid- hepatocytes
b) Superparamagnetic iron oxide- Kupffer cells
TREATMENT-
- Observation
- Excision incase of uncertainity of diagnosis
Exam Important
CLINICAL FEATURES-
- Patients are middle aged females on OCP
- Hepatic architecture is maintained.
- Asymptomatic
- Multiple nodule present
INVESTIGATIONS-
- Ultrasound shows solid mass
- CECT (IOC) shows central stellate scarring and hypervascular lesion.
- FNH contains hepatocytes & Kupffer cells.
- Angiography- spoke wheel/ cart wheel appearance
- MRI uses liver specific contrast agents to determine hepatocellular origin of FNH-
a) Gadoetic acid- hepatocytes
b) Superparamagnetic iron oxide- Kupffer cells
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