New

Molecular Motors & Markers

Renu Maurya

Molecular Motors & Markers

MOLECULAR MOTORS & MARKERS

MOLECULAR MOTORS:

  • Are protein with ATPase/GTPase activity that moves proteins, organelles & other cell parts from one part to other.
  • Generates energy via ATP/GTP for this force.
IMPORTANT CYTOSKELETAL MOLECULAR MOTORS:
 
Sl. no TYPE OF CYTOSKELETAL MOLECULAR MOTOR DESCRIPTION
 1.  Kinesin 
  • An ATPase – Uses ATP hydrolysis.
  • Involved in axoplasmic transport.
  • Moves vesicles towards the plus end of microtubules
 2.  Dynein
  • An ATPase.

Two types:

  • Cytosolic dynein – 
  • Involved in axoplasmic flow.
  • Moves vesicles towards the minus end of microtubules.
  • Axonemal dynein – 
  • Power ciliary & flagellar movement’
 3.  Dynamin
  • A GTPase – Uses GTP.
  • Involved in endocytosis.
 4.  Myosin
  • An ATPase – Uses ATP.
  • Involved in muscle contraction along with actin.
IMPORTANT CELLULAR MARKERS:
  • Cellular markers are specific enzyme proteins acting as markers for particular organelle.
ORGANELLE MARKERS
Mitochondria ATP synthase, Creatine kinase, Glutamate dehydrogenase
Plasma membrane  5‘ -Nucleotidase, Adenyl cyclase, Na+K+ATP’ase
Lysosome Acid phosphatase 
Golgi apparatus Galactosyl transferase, Golgi mannosidase II, Sialyl transferase. 
Peroxisome Catalase
Cytosol Lactate dehydrogenase 

Exam Important

MOLECULAR MOTORS:

  • Are proteins produce force for inter-cellular movements.
IMPORTANT CYTOSKELETAL MOLECULAR MOTORS:
  • Kinesin
  • Dynein
  • Dynamin
  • Myosin
IMPORTANT CELLULAR MARKERS:
ORGANELLE MARKERS
Mitochondria ATP synthase, Creatine kinase, Glutamate dehydrogenase
Plasma membrane  5‘ -Nucleotidase, Adenyl cyclase, Na+K+ATP’ase
Lysosome Acid phosphatase 
Golgi apparatus Galactosyl transferase, Golgi mannosidase II, Sialyl transferase. 
Peroxisome Catalase
Cytosol Lactate dehydrogenase
Don’t Forget to Solve all the previous Year Question asked on Molecular Motors & Markers

Exit mobile version