Question
Which of the following can eliminate free radicals from the body?
| A. | Glutamate |
| B. |
Glutathione |
| C. |
Selenium |
| D. |
Vitamin A |
|
Correct Answer � B Explanation |
 |
Glutathione (GSH):
– A tripeptide of glutamate, cysteine, & glycine.
– Acts as a major intracellular antioxidant.
Mechanism:
– Neutralizes free radicals like superoxide & hydrogen peroxide.
– Glutathione peroxidase uses GSH to convert hydrogen peroxide → water, forming oxidized glutathione (GSSG).
– Glutathione reductase regenerates GSH using NADPH.
– Protects RBCs, liver, & many tissues from oxidative damage.
Incorrect Options:
A. Glutamate:
– Excitatory neurotransmitter, not directly involved in radical detox.
C. Selenium:
– Trace mineral & cofactor for glutathione peroxidase; supports but isn’t a direct scavenger.
D. Vitamin A:
– Important for vision & health; some antioxidant properties but less effective than glutathione in radical elimination.