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MCQ – 24465

Question

Which of the following statements regarding calcium handling and parathyroid hormone (PTH) is correct?

A.

Calcium reabsorption in the kidney occurs only in the proximal convoluted tubule (PCT)

B.

Calcium reabsorption in the kidney is hormonally regulated in the distal convoluted tubule (DCT)

C.

Parathyroid hormone (PTH) directly increases calcium absorption from the intestine

D.

PTH enhances the action of calcitonin

Show Answer

Correct Answer » B

Explanation

  • The distal convoluted tubule (DCT) is the key regulatory site for calcium reabsorption.
  • PTH acts here to increase calcium reabsorption via active transport mechanisms.
  • This is the clinically and exam-relevant site.

Why Other Options are Incorrect

A. Calcium reabsorption occurs only in PCT 

  • Incorrect because calcium is reabsorbed in multiple segments:
    • PCT, thick ascending limb, and DCT
  • Also, PCT is not hormonally regulated

C. PTH directly increases intestinal calcium absorption 

  • PTH acts indirectly via vitamin D (calcitriol)

D. PTH enhances calcitonin 

  • PTH and calcitonin have opposite actions
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