MCQ – 4186

Correct Answer » C Explanation

The recurrent ulcers over the glans that heal with hyperpigmentation in sexually active males are suggestive of genital herpes, also known as herpes-genitalis. Genital herpes is a sexually transmitted infection caused by the herpes simplex virus (HSV), and it typically presents with painful, recurrent ulcers or sores in the genital area.

Genital herpes is a common sexually transmitted infection, and it is caused by two types of herpes simplex viruses: HSV-1 and HSV-2. While HSV-1 is commonly associated with oral herpes (cold sores), it can also cause genital herpes through oral-genital contact. HSV-2 is the primary cause of genital herpes and is typically transmitted through sexual contact with an infected individual.

The classic presentation of genital herpes includes small, painful, and shallow ulcers on or around the genitals, which can include the glans in males. These ulcers may last for several days before healing, and they may recur intermittently over time.

Reasons why the other options are incorrect:

A. Aphthous ulcer: Aphthous ulcers, also known as canker sores, are recurrent and painful shallow ulcers that commonly occur on the non-keratinized mucosal surfaces of the mouth, such as the inner lips, cheeks, tongue, and soft palate.

While they are not typically associated with the genital area, they may have a similar appearance to genital herpes ulcers. However, aphthous ulcers are not related to sexual activity and do not heal with hyperpigmentation.

B. Fixed drug eruptions: Fixed drug eruptions are a type of drug-induced skin reaction that leads to the development of well-defined, round or oval-shaped, dusky red or purple patches or ulcers on the skin or mucous membranes.

These eruptions are often caused by a particular medication and tend to recur at the same site with each exposure to the causative drug. Fixed drug eruptions do not typically present with ulcers in the genital area, and they do not have a specific association with sexual activity.

D. Chlamydial infection: Chlamydia is a common sexually transmitted bacterial infection caused by the bacterium Chlamydia trachomatis. While it can cause various symptoms in both males and females, such as urethritis, cervicitis, and pelvic inflammatory disease, it does not typically present with recurrent ulcers over the glans in males.

Chlamydial infection is diagnosed through laboratory tests, and it is usually treated with antibiotics.