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MCQ – 69035

Question

A patient presents with patchy hair loss and noticeably velvety skin. Which of the following is the most likely diagnosis?

A.

Alopecia Areata

B.

Trichotelomania

C.

Hyperthyroidism

D.

Adenoma sebacicum

Show Answer

Correct Answer » A

Explanation

Anatomical Role
– Patchy hair loss involves the hair follicles, typically sparing follicle structure but causing non-scarring alopecia.
– Skin texture changes like velvety skin suggest associated autoimmune or endocrine involvement.

Clinical Reasoning for the Correct Answer
Alopecia Areata is a common cause of patchy non-scarring hair loss, characterized by well-demarcated circular bald patches.
– Patients may have coexisting autoimmune conditions or skin changes like velvety, smooth skin due to autoimmune or trophic changes, supporting this diagnosis.
– Velvety skin can also occur due to localized areas of lichenification or subtle thickening often associated with alopecia areata.
– No signs of hair shaft damage or behavioral causes are described, favoring alopecia areata.

Why Option A is Correct
– Patchy, well-defined non-scarring hair loss matches alopecia areata.
– Velvety skin texture may occur due to autoimmune inflammation affecting the scalp skin.

Why Option B is Incorrect
– Trichotillomania is a psychogenic hair-pulling disorder with irregular, broken hair shafts and uneven alopecia patches.
– It lacks velvety skin and often shows “frayed” hair shafts on examination.
– The patient history usually reveals compulsive hair pulling.

Why Option C is Incorrect
– Hyperthyroidism usually causes diffuse hair thinning and fine, soft hair, without patchy hair loss.
– Skin in hyperthyroidism is classically warm, moist, and smooth, not velvety.
– Additional systemic signs are expected (tachycardia, heat intolerance).

Why Option D is Incorrect
– Sebaceous adenoma is a benign tumor of sebaceous glands, presenting as a yellowish papule or nodule, not patchy hair loss.
– It does not cause diffuse or patchy alopecia or skin texture changes like velvety skin.
– This is a localized lesion, not a scalp-wide condition.

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