Question
| A. |
Estrogen ointment |
| B. |
Antihistamines |
| C. |
Tamoxifen |
| D. |
None |
|
Correct Answer » A Explanation |
 |
Vulvar atrophy is a manifestation of Genitourinary Syndrome of Menopause (GSM) caused by estrogen deficiency. Patients commonly present with vulvar itching, dryness, burning, dyspareunia, and irritation.
Topical estrogen therapy is the treatment of choice for symptomatic vulvovaginal atrophy. It restores the vaginal and vulvar epithelium, improves lubrication, and relieves itching and other symptoms with minimal systemic absorption.
Explanation of Each Option
A. Topical estrogen ointment (estrogen cream) – Correct. It is the first-line treatment for symptomatic vulvar/vaginal atrophy due to estrogen deficiency.
B. Antihistamines – Incorrect. They may provide temporary relief of itching but do not treat the underlying estrogen deficiency.
C. Tamoxifen – Incorrect. Tamoxifen is a Selective Estrogen Receptor Modulator (SERM) used in estrogen receptor-positive breast cancer and may actually worsen vaginal atrophy.