Question
Which of the following statements is true about the following dose response?
| A. |
Both A and B are full agonists |
| B. |
B is more potent than A |
| C. |
C is a noncompetitive antagonist |
| D. |
C is a competitive antagonist |
Show Answer
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Correct Answer � A Explanation |
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Ans: A. Both A and B are full agonists
Given dose response curve:
A & B:
- Full agonists.
- Have maximum possible efficacy.
Potency:
- A>B>C.
Efficacy:
- A=B>C.
Details on C drug:
- Not an antagonist.
- it is Partial agonist.
Potency:
- Drug producing the same response at a lower dose is more potent.
- More DRC towards left –> Greater potency.
- Hence A>B>C>D.