Question
A 35 years old female presented with an adnexal mass. CA125 was slightly raised, CA19-9 was normal and LDH was elevated. The tumor was resected and the gross and microscopic image was as given below. What is the most likely diagram?
| A. |
Papillary serous cystadenocarcinoma |
| B. |
Dysgerminoma |
| C. |
Teratoma |
| D. |
Choriocarcinoma |
Show Answer
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Correct Answer � B Explanation |
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Ans: B. Dysgerminoma
- Tumor described is suggestive of dysgerminoma.
Dysgerminomas:
- Unilateral tumors ((80% to 90%) ranging in size from barely visible nodules to masses fills the entire abdomen.
- Solid yellow-white to a gray-pink appearance on slicing.
- Soft & fleshy.
Histology:
- Composed of large vesicular cells with clear cytoplasm, well-defined cell boundaries & centrally placed regular nuclei.
- Tumor cells grow in sheets or cords separated by scant fibrous stroma infiltrated by mature lymphocytes & occasional granulomas.