Question
True about protein A of Staphlococus aureus ‑
| A. | Causes opsonization |
| B. |
Binds to Fc part of IgG |
| C. |
Stimulate phagocytosis |
| D. |
T-cell mitogen |
Show Answer
|
Correct Answer � B Explanation |
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Ans.B. Binds to Fc part of IgG
- Protein ‘A’ binds to Fc terminal of IgG (IgG 1, 2 & 4 but not IgG3) and prevents opsonophagocytosis by PMNs.
- It is a B-cell mitogen. It is chemotactic, anti-complementary and antiphagocytic.