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MCQ – 80220

Question

Radioiodine preferred in treatment in  
A.

Young patients

B.

Pregnancy

C.

Recent onset of toxic goiter

D.

Post surgery for papillary thyroid cancer

Show Answer

Correct Answer » D

Explanation

Radioiodine (I-131) is used in both benign and malignant thyroid conditions. However, its preferred and standard indication is in differentiated thyroid cancers after surgery.

Explanation of the Correct Answer:
After thyroidectomy for papillary thyroid carcinoma, radioiodine is used for:

  • Ablation of residual thyroid tissue
  • Treatment of microscopic residual disease
  • Management of metastasis
  • Facilitating follow-up using thyroglobulin levels

Thus, it is a standard adjuvant therapy in papillary thyroid cancer.

Explanation of Other Options:

A. Young patients
Radioiodine is relatively avoided due to long-term risks (e.g., secondary malignancy). Not preferred.

B. Pregnancy
Absolutely contraindicated as it crosses the placenta and destroys fetal thyroid.

C. Recent onset of toxic goiter
First-line treatment is antithyroid drugs (e.g., Methimazole). Radioiodine is used later, not preferred initially.

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