Question
Cofactors for glutamate dehydrogenase:
| A. | NAD+ |
| B. |
FAD |
| C. |
FMN |
| D. |
FADH2 |
Show Answer
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Correct Answer � A Explanation |
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Anaerobic Dehydrogenases are the enzymes that catalyze the removal of hydrogen from a substrate but oxygen cannot act as the hydrogen acceptor. They, therefore, require coenzymes as acceptors of the hydrogen atoms.
When the substrate is oxidized, the coenzyme is reduced.
NAD+ is derived from nicotinic acid, a member of the vitamin B complex. The NAD+ linked dehydrogenases are-
- Glyceraldehyde-3-phosphate dehydrogenase
- Isocitrate dehydrogenase
- Malate dehydrogenase
- Glutamate dehydrogenase
- Beta hydroxy acyl CoA dehydrogenase
- Pyruvate dehydrogenase
- Alpha-ketoglutarate dehydrogenase