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MCQ – 84812

Question

Assertion: B12 deficiency causes subacute combined degeneration of the spinal cord.
Reason: B12 deficiency causes degeneration of both the ascending and descending tracts of the spinal cord.
A.
Both assertion and reason are true and reason is correct explanation of assertion.
B.
Both assertion and reason are true and reason is not the correct explanation of assertion.
C.
Assertion is true and reason is false.
D. Both assertion and reason is false.
Show Answer

Correct Answer » A

Explanation

  • Subacute combined degeneration (SCD) is a neurological complication of vitamin B12 deficiency.
  • It occurs due to demyelination involving:
    • Posterior (dorsal) columns → ascending sensory tracts
    • Lateral corticospinal tracts → descending motor tracts
  • Since both ascending and descending tracts are affected, it is called “combined” degeneration.

Thus:

  • Assertion is true.
  • Reason is also true.
  • The reason correctly explains the assertion.
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