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MCQ – 84929

Question

DOC for bacterial vaginosis in pregnancy
A.

Clindamycin

B.

Erythromycin

C.

Rovamycin

D.

Metronidazole

Show Answer

Correct Answer » D

Explanation

  • Bacterial vaginosis (BV)is caused by:
    • Overgrowth of anaerobes (e.g., Gardnerella vaginalis)
  • Treatment aims to eradicate anaerobic bacteria

Metronidazole

    • First-line drug for BV
    • Effective against anaerobes
    • Safe in pregnancy (especially after first trimester; now widely considered safe overall)

Explanation of Other Options

  • A. Clindamycin
    • Alternative drug
    • Used if metronidazole not tolerated
  • B. Erythromycin
    • Not used for BV
    • Ineffective against typical BV organisms
  • C. Rovamycin (Spiramycin)
    • Used in toxoplasmosis in pregnancy
    • Not for BV

Bacterial Vaginosis

  • Cause: Gardnerella + anaerobes
  • Features:
    • Thin, gray discharge
    • Fishy odor (positive whiff test)
    • Clue cells
  • Treatment:
    • DOC → Metronidazole
    • Alternative → Clindamycin
  • Pregnancy point:
    • BV associated with:
      • Preterm labor
      • PROM
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