Question
| A. |
BSL 1 |
| B. |
BSL 2 |
| C. |
BSL 3 |
| D. |
BSL 4 |
|
Correct Answer » C Explanation |
 |
SARS-CoV-2 is a Risk Group 3 pathogen. While routine diagnostic testing (e.g., RT-PCR on inactivated specimens) can be performed in a BSL-2 laboratory, viral isolation, culture, propagation of live virus, and aerosol-generating procedures require a BSL-3 laboratory.
Why Other Options are Incorrect
A. BSL-1 – Used for non-pathogenic organisms that do not cause disease in healthy humans (e.g., non-pathogenic E. coli); not suitable for SARS-CoV-2.
B. BSL-2 – Suitable for routine diagnostic testing of inactivated specimens, but not for culturing or handling live SARS-CoV-2.
D. BSL-4 – Reserved for highly dangerous pathogens such as Ebola, Marburg, and Variola (smallpox); SARS-CoV-2 does not require BSL-4 containment for routine research or diagnostic work.