Question
A 50-year-old woman has multiple lytic lesions in the skull. Which of the following is the least likely cause?
| A. | Multiple myeloma |
| B. |
Eosinophilic granuloma |
| C. |
Metastasis |
| D. |
Hyperparathyroidism |
Show Answer
|
Correct Answer � B Explanation |
 |
Answer B) Eosinophilic granuloma
All of the above conditions cause lytic lesion in the skull but eosinophilic granuloma is seen in a younger age group (5-15 years old).
Causes of lytic lesions in skull:
Metastasis
Eosinophilic granuloma (geographic lytic lesions in vault of skull with bevelled edges)
Lymphoma
Langerhans Cell Histiocytosis (permeative lesions)
Tuberculosis
Hyperparathyroidism (salt and pepper skull)
Osteomyelitis
Radiation
Multiple myeloma (punched out lytic lesion)
