Site icon New

MCQ – 89520

Question

Which of the following drugs is used for the long term management of obesity
A.

Sibutramine

B.

Fenfluramine

C.

Metformin

D.

Liraglutide

Show Answer

Correct Answer » D

Explanation

Liraglutide is a GLP-1 (Glucagon-Like Peptide-1) receptor agonist.

Mechanism:

  • ↑ Satiety (acts on hypothalamus)

  • ↓ Appetite

  • Delays gastric emptying

Indication:

  • Chronic weight management

  • BMI ≥30 kg/m²

  • BMI ≥27 kg/m² with comorbidities

Brand used for obesity: Saxenda


Why Other Options Are Wrong

A. Sibutramine

  • Serotonin–norepinephrine reuptake inhibitor

  • Withdrawn worldwide

  • Causes cardiovascular events

B. Fenfluramine

  • Serotonin releasing drug

  • Withdrawn due to valvular heart disease & pulmonary hypertension

C. Metformin

  • Used for Type 2 diabetes

  • Causes mild weight loss but not approved for obesity treatment

Exit mobile version