Question
If the RNA sequence is CAAGGU. What is the sequence of the template strand?
| A. |
CAAGGT |
| B. |
GTTCCA |
| C. |
ACCTTG |
| D. |
TGGAAC |
Show Answer
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Correct Answer » C Explanation |
 |
RNA is synthesized using the DNA template strand in the 3′ to 5′ direction.
– RNA bases pair with the template strand via complementary base pairing: A (adenine) pairs with T (thymine) in DNA, U (uracil) pairs with A, G (guanine) pairs with C (cytosine), and C pairs with G.
– Given RNA sequence: 5′-CAAGGU-3′, this corresponds to bases: C-A-A-G-G-U.
– The DNA template strand must be complementary and antiparallel, so it runs 3′-GTTCCA-5′ (which is 5′-ACCTTG-3′ when written 5′ to 3′).
– Therefore, template strand sequence is 5′-ACCTTG-3′.