Question
Which is the most specific causative agent of Rabies?
| A. | Lyssavirus serotype 1 |
| B. |
Lyssavirus serotype 2 |
| C. |
Lyssavirus serotype 3 |
| D. |
Lyssavirus serotype 4 |
Show Answer
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Correct Answer � A Explanation |
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Rabies is a fatal viral disease affecting the central nervous system (CNS), caused by the Rabies virus (RABV), which belongs to the Lyssavirus genus of the Rhabdoviridae family.
- Lyssavirus serotype 1 is the classical Rabies virus, responsible for the majority of human and animal rabies cases worldwide.
- Other Lyssavirus serotypes (2, 3, 4, etc.) are found in bats and other animals but are less commonly associated with human rabies.
Reasons to Rule Out Other Options:
B. Lyssavirus serotype 2
- This includes Lagos Bat Virus (LBV), which rarely causes human infections and is mainly found in bats in Africa.
C. Lyssavirus serotype 3
- Includes Mokola virus, another African Lyssavirus, which is not a common cause of human rabies.
D. Lyssavirus serotype 4
- Includes Duvenhage virus, which has caused only a few reported human cases from bat bites.