Short Quiz on PASSIVE TRANSPORT

Instruction

1. This Test has 5 Questions 
2. There is 1 Mark for each correct Answer

MCQ – 1

According to Fick’s law of diffusion, particle flux will decrease if there is an increase in the:

Particle’s concentration difference across the membrane

Thickness of the Membrane

Area of the membrane

Temperature of the solution

Explanation :
According to Fick’s law of diffusion, particle flux is inversely proportional to the thickness of the membrane and directly proportional to the area of the membrane, the concentration difference across the membrane, and the diffusion coefficient.
The diffusion coefficient depends on the physical properties of the particle and the membrane through which it is diffusing.
In general, the larger the diameter of the particle, the slower the rate of diffusion. Increasing temperature will increase the rate of diffusion.

MCQ – 2

Urea is transported in the renal tubules by the following mechanism:

Active transport

Passive transport

Facilitated diffusion

Both A and B

Explanation :
Urea transport is mediated by urea transporters, presumably by facilitated diffusion.
There are at least four isoforms of the transport protein UT-A in the kidneys (UT-A1 to UT-A4); UT-B is found in erythrocytes and in the descending limbs of the vasa recta.
Urea transport in the collecting duct is mediated by UT-A1 and UT-A3, and both are regulated by vasopressin.

MCQ – 3

Which of the following does not affect rate of diffusion?

Area of diffusion

Concentration gradient

Time

None of the above

Explanation :

The magnitude of the diffusing tendency from one region to another is directly proportionate to the cross-sectional area across which diffusion is taking place and the concentration gradient, or chemical gradient, which is the difference in concentration of the diffusing substance divided by the thickness of the boundary (Fick’s law of diffusion). 

Ref:Ganong’s Review of Medical Physiology 23rd edition, Chapter 1.


MCQ – 4

Fick’s law is associated with which of the following functions?

Osmosis

Phagocytosis

Diffusion

None of the above

Explanation :
The magnitude of the diffusing tendency from one region to another is directly proportionate to the cross-sectional area across which diffusion is taking place and the concentration gradient, or chemical gradient, which is the difference in concentration of the diffusing substance divided by the thickness of the boundary (Fick’s law of diffusion).
Ref: Ganong’s Review of Medical Physiology 23rd edition, Chapter 1.

 


MCQ – 5

Through which of the following means of transport is folic acid absorbed in proximal jejunum?

Facilitated diffusion

Active transport

Passive transport

Both active and passive transport

Explanation :

Folic acid is absorbed in the proximal jejunum through both active and passive transport. First step in the absorption of folate involves hydrolysis of pteroyl polyglutamates into pteroyl monoglutamate by conjugase enzyme located in the intestinal mucosa. Next step involves absorption of pteroyl monoglutamate through active carrier mediated transport. Besides this, pharmacologic doses of folate are also absorbed passively by facilitated diffusion.

  • After absorption from the lumen into the enterocyte intracellular enzymes reduce and methylate the monoglutamate to produce metabolically active form of folic acid. This form is then absorbed into circulation by simple diffusion. 
  • Most of the vitamins are absorbed passively. Cyanocobalamin is the only vitamin that that depends on active transport for its absorption. Folic acid and thiamine are the only other vitamins for which active mechanism of absorption is known.

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