Question
A 20 year old female is diagnosed to have molar pregnancy. All of the following are features of partial mole, EXCEPT:
| A. |
Fetus is present |
| B. |
Amnion is present |
| C. |
Karyotype is usually 69 XXY |
| D. |
Greater risk of persistent trophoblastic disease |
Show Answer
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Correct Answer � D Explanation |
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In a case of partial mole there is only 1-5% risk of development of persistent trophoblastic disease. There is a 15–20% risk for developing this in cases of complete mole.
Features of partial mole are:
- Karyotype is usually 69,XXX or 69,XXY
- Fetus, amnion and fetal red blood cells are often present
- Villous edema could be focal or diffuse
- Trophoblastic proliferation could be variable
- 1-5% risk of developing persistent trophoblastic disease
Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 11. Gestational Trophoblastic Disease.