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MCQ – 136644

Question

A histological section is given below. Identify the marked cells.

A. Stellate Cells
B. Basket Cells
C.

Purkinje Cells

D.

Granular Cells

Show Answer

Correct Answer � C

Explanation

  • The marked cells are large, flask-shaped neurons located in a distinct single layer between a densely cellular inner layer and a pale outer layer — this is classic for Purkinje cells in the cerebellar cortex.

  • Their dendrites project upward into the molecular layer, and axons pass downward into the deep cerebellar nuclei.

Histological Layers of the Cerebellar Cortex:

  1. Molecular Layer (Outer):

    • Sparse cells: stellate and basket cells

    • Contains dendritic trees of Purkinje cells and parallel fibers from granule cells

  2. Purkinje Cell Layer (Middle):

    • Single row of large Purkinje cells

    • Only output neurons of the cerebellar cortex (inhibitory: GABAergic)

  3. Granular Layer (Inner):

    • Packed with small granule cells

    • Axons ascend to molecular layer → bifurcate into parallel fibers

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