Question
2025 Nobel Prize in Medicine is awarded for?
| A. | Peripheral immune tolerance |
| B. | Micro RNA |
| C. |
mRNA vaccine technology |
| D. |
Targeted immunotherapy |
|
Correct Answer � A Explanation |
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The 2025 Nobel Prize in Physiology or Medicine was awarded to Shimon Sakaguchi, Diane Mathis, and Christophe Benoist.
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The award recognized their pioneering discoveries in the field of peripheral immune tolerance, especially the identification and role of regulatory T cells (Tregs) in preventing autoimmune diseases.
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Their work demonstrated how the immune system can be selectively suppressed to prevent attacking the body’s own cells outside the thymus.
Why other options are incorrect:
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Micro RNA: Awarded earlier in 2006 (RNA interference by Fire and Mello), not in 2025.
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mRNA vaccine technology: Recognized in the 2023 Nobel Prize (Katalin Karikó and Drew Weissman).
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Targeted immunotherapy: Acknowledged in the 2018 Nobel Prize (James Allison and Tasuku Honjo for checkpoint inhibitors), not 2025.