Question
Immune checkpoint inhibitor among the following is?
| A. |
Ranibizumab
|
| B. |
Avelumab
|
| C. |
Abciximab
|
| D. |
Denosumab
|
Show Answer
|
Correct Answer � B
Explanation
|
|
Ans.B. Avelumab is an immune checkpoint inhibitor.
Immune checkpoint inhibitors inhibit proteins, When these proteins are blocked, the brake on the immune system is released and T cells can kill cancer cells more efficiently.
Immune checkpoint inhibitors-
PD-L1 (protein on normal and many cancer cells) inhibitors: Atezolizumab, Avelumab, Durvalumab.
PD-1 (checkpoint protein on T cells) inhibitors: Pembrolizumab, Nivolumab.
CTLA-4 (checkpoint protein on T cells) inhibitor: Ipilimumab.
