Question
Which among the following is the allosteric activator of acetyl CoA carboxylase ?
| A. |
Malonyl CoA |
| B. |
Acetyl CoA |
| C. |
Citrate |
| D. |
Biotin |
Show Answer
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Correct Answer � C Explanation |
 |
Ans.C. Citrate
Acetyl-CoA carboxylase is an allosteric enzyme and is activated by citrate, which increases in concentration in the well-fed state and is an indicator of a plentiful supply of acetyl-CoA.
Citrate promotes the conversion of the enzyme from an inactive dimer to an active polymeric form, with a molecular mass of several million.