Question
Commonest type of emphysema is ‑
| A. | Centriacinar |
| B. | Obstructed |
| C. |
Irregular |
| D. |
Panacinar |
Show Answer
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Correct Answer » A Explanation |
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A. Centriacinar
Emphysema:
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Emphysema is a form of chronic obstructive pulmonary disease (COPD) characterized by destruction of alveolar walls and airspace enlargement.
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It is classified based on which part of the acinus is affected.
Types of Emphysema:
| Type | Affected Area | Common Cause | Typical Location |
|---|---|---|---|
| Centriacinar (Centrilobular) | Respiratory bronchioles(central portion) | Smoking, chronic bronchitis | Upper lobes |
| Panacinar | Entire acinus uniformly | α1-antitrypsin deficiency | Lower lobes |
| Irregular | Scarring (post-inflammatory) | Often asymptomatic, incidental | Irregular distribution |
Centriacinar Is the Most Common:
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Most frequently seen in smokers
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Strongly associated with chronic inflammation, oxidative stress, and protease-antiprotease imbalance
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Involves the upper lobes and the central acinus (respiratory bronchioles)