Question
Lipogenesis occurs in ‑
| A. |
Liver |
| B. |
Skeletal muscles |
| C. |
Myocardium |
| D. |
Lungs |
Show Answer
|
Correct Answer » A Explanation |
|
- Lipogenesis is the synthesis of fatty acids from excess carbohydrates.
- The liver is the principal site of lipogenesis in humans.
- Adipose tissue also contributes, but liver is the main organ.
Important Enzymes
- Acetyl-CoA carboxylase — rate-limiting enzyme
- Fatty acid synthase
Stimulated By
- Insulin
- High carbohydrate intake
Inhibited By
- Glucagon
- Fasting
- Epinephrine
Why Other Options Are Incorrect
- Skeletal muscle: Mainly uses fatty acids for energy.
- Myocardium: Predominantly performs fatty acid oxidation.
- Lungs: Not a significant site of lipogenesis.
