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MCQ – 83383

Question

Lipogenesis occurs in ‑

A.

Liver

B.

Skeletal muscles

C.

Myocardium

D.

Lungs

Show Answer

Correct Answer » A

Explanation

  • Lipogenesis is the synthesis of fatty acids from excess carbohydrates.
  • The liver is the principal site of lipogenesis in humans.
  • Adipose tissue also contributes, but liver is the main organ.

Important Enzymes

  • Acetyl-CoA carboxylase — rate-limiting enzyme
  • Fatty acid synthase

Stimulated By

  • Insulin
  • High carbohydrate intake

Inhibited By

  • Glucagon
  • Fasting
  • Epinephrine

Why Other Options Are Incorrect

  • Skeletal muscle: Mainly uses fatty acids for energy.
  • Myocardium: Predominantly performs fatty acid oxidation.
  • Lungs: Not a significant site of lipogenesis.
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