MCQ – 83383

Lipogenesis occurs in ‑

Correct Answer » A Explanation

• Lipogenesis is the synthesis of fatty acids from excess carbohydrates.
• The liver is the principal site of lipogenesis in humans.
• Adipose tissue also contributes, but liver is the main organ.

Important Enzymes

• Acetyl-CoA carboxylase — rate-limiting enzyme
• Fatty acid synthase

Stimulated By

• Insulin
• High carbohydrate intake

Inhibited By

• Glucagon
• Fasting
• Epinephrine

Why Other Options Are Incorrect

• Skeletal muscle: Mainly uses fatty acids for energy.
• Myocardium: Predominantly performs fatty acid oxidation.
• Lungs: Not a significant site of lipogenesis.