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MCQ – 85375

Question

Pauci-immune crescentic glomerulonephritis is associated with:
A.
Microscopic polyangiitis 
B.  Systemic lupus erythematosus
C.

Polyarteritis nodosa

D.

Henoch-Schonlein purpura 

Show Answer

Correct Answer � A

Explanation

Ans.A. Microscopic polyangiitis 

Crescentic glomerulonephritis is of three types:

Type I, Type II, Type III

               Type I RPGN
                   Type II RPGN
           TypeIII RPGN (pauci immune)
 
  • idiopathic
  • Goodpasture’s syndrome.

 

  •   idiopathic
  •    Post-infectious
  •    Henoch chonlein purpura.
  •   idiopathic.
  •    ANCA associated.
  •    Wegener’s granulomatosis.
  •    microscopic polyangiitis.
Immunofluorescence finding
Immunofluorescence finding
Immunofluorescence finding
• Linear GBM deposits of IgG and C3 
• “Lumpy bumpy” granular pattern of staining. 
• No immunoglobulin or complement deposits in GBM
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