Question
The 14-year-old daughter of a circus contortionist says that her skin scars and bruises easily. Physical examination reveals the findings seen below .
This patient most likely has an inherited defect in which of the following:
| A. | Fibrillin |
| B. |
Laminin |
| C. |
Fibronectin |
| D. |
Collagen |
Show Answer
|
Correct Answer � D Explanation |
 |
Ans. D. Collagen
Ehlers-Danlos syndrome is a heritable connective tissue disease associated with abnormal collagen formation. EDS usually manifests clinically as over-flexible (hypermobile) joints, over-elastic (hyperelastic) skin, and fragile tissue susceptible to bruising, wounding, and hemarthrosis.