Question
The 14-year-old daughter of a circus contortionist says that her skin scars and bruises easily. Physical examination reveals the findings seen below .
This patient most likely has an inherited defect in which of the following:
| A. |
Fibrillin
|
| B. |
Laminin
|
| C. |
Fibronectin
|
| D. |
Collagen
|
Show Answer
|
Correct Answer � D
Explanation
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|
Ans. D. Collagen
Ehlers-Danlos syndrome is a heritable connective tissue disease associated with abnormal collagen formation. EDS usually manifests clinically as over-flexible (hypermobile) joints, over-elastic (hyperelastic) skin, and fragile tissue susceptible to bruising, wounding, and hemarthrosis.
