Question
In the following graph given below the red line depicts which of the following situation
| A. | Reaction with a non competitive inhibitor |
| B. |
Reaction with a Allosteric inhibitor |
| C. |
Reaction with a suicide inhibitor |
| D. |
Reaction with competitive inhibitor |
Show Answer
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Correct Answer � A Explanation |
 |
Answer- A
Red line in the graph represents a reaction with Noncompetitive inhibitor.
The above graph is called; Line weaver-Burk plot ; double reciprocal; plot.
1/v0 is plotted versus 1/S and a straight line is obtained.
This plot can be used to calculate Km and V max as well as to determine the mechanism of action of enzyme inhibitors.
In non-competitive inhibition, V max decreases (or 1/V max increases) but Km is unchanged
