Question
In the following graph given below the red line depicts which of the following situation
| A. |
Reaction with a non competitive inhibitor
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| B. |
Reaction with a Allosteric inhibitor
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| C. |
Reaction with a suicide inhibitor
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| D. |
Reaction with competitive inhibitor
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Show Answer
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Correct Answer � A
Explanation
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Answer- A
Red line in the graph represents a reaction with Noncompetitive inhibitor.
The above graph is called; Line weaver-Burk plot ; double reciprocal; plot.
1/v0 is plotted versus 1/S and a straight line is obtained.
This plot can be used to calculate Km and V max as well as to determine the mechanism of action of enzyme inhibitors.
In non-competitive inhibition, V max decreases (or 1/V max increases) but Km is unchanged
