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MCQ – 95099

Question

Which of the following statements about bone structure and composition is not true?
A.

Osteocytes are the major cell type in mature bone

B.

Collagen is synthesized in bone osteoblasts

C.

Bone mainly contains type 2 collagen

D.

Calcium phosphate is one of the major inorganic minerals

Show Answer

Correct Answer � C

Explanation

Bone mainly contains type 2 collagen.

This is false because bone primarily contains type 1 collagen, not type 2. Type 1 collagen is the most abundant collagen type in the extracellular matrix of bone, providing structural support and tensile strength. Type 2 collagen, on the other hand, is predominantly found in cartilage, where it plays a crucial role in maintaining cartilaginous structure and resilience.

Reasons for ruling out other options are-

A. Osteocytes are the major cell type in mature bone – This is true as osteocytes, derived from osteoblasts, are the most abundant cell type in mature bone. They reside in lacunae and are crucial for the maintenance and turnover of bone tissue.

B. Collagen is synthesized in bone osteoblasts – This is correct. Osteoblasts are the bone cells responsible for synthesizing the collagen matrix and other components that form the structural framework of bone tissue.

D. Calcium phosphate is one of the major inorganic minerals – This statement is accurate. The primary inorganic component of bone is hydroxyapatite, which is a calcium phosphate mineral. This mineral gives bone its hardness and strength to support the body’s structures.


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