Question
Which drug decreases the bone resorption in osteoporosis?
| A. |
Teriparatide |
| B. | Risedronate |
| C. |
Cortisone |
| D. |
Cimetidine |
|
Correct Answer � B Explanation |
 |
Ans. B – Risedronate
A. Teriparatide is an anabolic agent that is a recombinant form of parathyroid hormone (PTH). Instead of decreasing bone resorption, it actually increases bone formation by stimulating osteoblast activity.
B. Risedronate belongs to a class of drugs called bisphosphonates. Bisphosphonates are antiresorptive agents that inhibit osteoclast-mediated bone resorption, thus increasing bone density and reducing the risk of fractures in patients with osteoporosis
C. Cortisone is a corticosteroid, which when taken in excess or for prolonged periods, can lead to bone loss and increase the risk of osteoporosis. It does not decrease bone resorption; instead, it can contribute to increased bone resorption.
D. Cimetidine is an H2 receptor antagonist used to reduce stomach acid production, mainly in the treatment of ulcers and gastroesophageal reflux disease (GERD). It has no significant effect on bone resorption.
