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AIIMS PG Exam – 84931

Question

The adverse effect of Foscarnet includes all except-

A. Hypercalcemia

B. Hyperkalemia

C. Hypocalcemia

D. Hypokalemia

 

Show Answer

Correct Answer » B

Explanation

Ans. B. Hyperkalemia

Potential adverse effects of foscarnet include:-

* Renal impairment, hypo- or hypercalcemia, hypo- or hyperphosphatemia, hypokalemia, and hypomagnesemia.

* Penile ulceration associated with Foscarnet therapy may be due to a high level of ionized drug in the urine.

* Nausea, vomiting, anemia, the elevation of liver enzymes, and fatigue have been reported.

* The risk of anemia may be additive in patients receiving concurrent zidovudine.

* CNS toxicities include headache, hallucinations, and seizures.

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