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MCQ – 46042

Question

The most common presentation for IgA nephropathy  is:
A.

Nephritic syndrome

B.

Nephrotic syndrome

C.

Microscopic hematuria

D.

Repeated gross hematuria

Show Answer

Correct Answer » D

Explanation

  • IgA nephropathy (Berger disease) is characterized by deposition of IgA in the mesangium of the glomeruli.
  • It commonly presents after upper respiratory tract infection or gastrointestinal infection.

Explanation of the Correct Answer

  • The most characteristic and common presentationis:
    • Recurrent episodes of gross (visible) hematuria
    • Typically occurs within 1–2 days of infection (synpharyngitic hematuria)
  • This is a hallmark feature and helps differentiate it from post-streptococcal glomerulonephritis (which occurs after a latent period).

Explanation of Other Options

A. Nephritic syndrome

    • IgA nephropathy can present as nephritic syndrome, but this is not the most common presentation

B. Nephrotic syndrome

    • Rare in IgA nephropathy
    • More typical of diseases like minimal change disease, membranous nephropathy

C. Microscopic hematuria

    • Can occur, especially between episodes
    • However, the classical and most common presentation tested in exams is recurrent gross hematuria
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