Question
The most common presentation for IgA nephropathy is:
| A. |
Nephritic syndrome
|
| B. |
Nephrotic syndrome
|
| C. |
Microscopic hematuria
|
| D. |
Repeated gross hematuria
|
Show Answer
|
Correct Answer » D
Explanation
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|
- IgA nephropathy (Berger disease) is characterized by deposition of IgA in the mesangium of the glomeruli.
- It commonly presents after upper respiratory tract infection or gastrointestinal infection.
Explanation of the Correct Answer
- The most characteristic and common presentationis:
- Recurrent episodes of gross (visible) hematuria
- Typically occurs within 1–2 days of infection (synpharyngitic hematuria)
- This is a hallmark feature and helps differentiate it from post-streptococcal glomerulonephritis (which occurs after a latent period).
Explanation of Other Options
A. Nephritic syndrome
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- IgA nephropathy can present as nephritic syndrome, but this is not the most common presentation
B. Nephrotic syndrome
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- Rare in IgA nephropathy
- More typical of diseases like minimal change disease, membranous nephropathy
C. Microscopic hematuria
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- Can occur, especially between episodes
- However, the classical and most common presentation tested in exams is recurrent gross hematuria